Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.73 |
| ▸ | MTNR1A | P48039 | 14/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.66 |
| ▸ | NQO2 | P16083 | 4/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950254 | 0.97 | HDAC3 (0.71) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL23950258 | 0.93 | MTNR1A (0.69) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL23950141 | 0.87 | MTNR1A (0.69) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL16068348 | 0.83 | HDAC3 (0.73) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL8717163 | 0.82 | MTNR1A (0.74) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL20307244 | 0.81 | HDAC3 (0.70) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL23950140 | 0.80 | MTNR1A (0.71) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL5144427 | 0.80 | MTNR1A (1.00) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL16068372 | 0.79 | HDAC3 (0.68) | HDAC3HDAC6MTNR1AMTNR1BNQO2 | |
| SCHEMBL1067941 | 0.78 | MTNR1A (0.78) | HDAC3HDAC6MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323917-A1 | MELATONIN DERIVATIVES, METHOD THEREOF, AND USE THEREOF | XIAMEN NUOKANGDE BIOLOGICAL TECHNOLOGY CO., LTD. (CN) | 2021-10-21 | — | — | US | disclosed |
| US-20210323917-A1 | MELATONIN DERIVATIVES, METHOD THEREOF, AND USE THEREOF | XIAMEN NUOKANGDE BIOLOGICAL TECHNOLOGY CO., LTD. (CN) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323917-A1 | MELATONIN DERIVATIVES, METHOD THEREOF, AND USE THEREOF | MTNR1A, MTNR1B, INMT | HDAC3 3961/4885HDAC6 2208/4885MTNR1A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.