Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 4/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23943225 | 0.91 | PLG (0.44) | ADORA2AADORA1HSD17B14DHODHPLG | |
| SCHEMBL23925778 | 0.90 | CD274 (0.46) | ADORA2AADORA1HSD17B14DHODHPLG | |
| SCHEMBL3749641 | 0.80 | DHODH (0.45) | ADORA2AADORA1DHODHPDCD1LG2CD274 | |
| SCHEMBL23943229 | 0.77 | HSD17B14 (0.59) | ADORA2AADORA1HSD17B14GRM4KDM1A | |
| SCHEMBL3747145 | 0.76 | CD274 (0.38) | ADORA2AADORA1DHODHKDM1APDCD1LG2 | |
| SCHEMBL3759883 | 0.74 | KMO (0.46) | DHODHPDCD1LG2CD274 | |
| SCHEMBL3754181 | 0.73 | PLG (0.43) | PLGPLAUPDCD1LG2CD274PYGL | |
| SCHEMBL3759586 | 0.72 | HTT (0.47) | DHODHPDCD1LG2CD274CCNT1CDK9 | |
| SCHEMBL3757716 | 0.71 | EIF4E (0.39) | HSD17B14DHODHF10CD274 | |
| SCHEMBL3755649 | 0.71 | DHODH (0.47) | ADORA2AADORA1DHODHKDM1APDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150940-A1 | HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2023-05-18 | — | — | US | disclosed |
| WO-2021211974-A1 | HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150940-A1 | HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | ADORA2A 4678/4885ADORA1 4623/4885HSD17B14 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.