SCHEMBL23926355

SCHEMBL23926355

Cc1ccc(OCc2ccccc2)c(C(O)C2CCCN2)n1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.38
SLC6A3 Q01959 4/20 0.38
SLC6A4 P31645 3/20 0.38
HTR1A P08908 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30118946 1.00 SLC6A2 (0.38) SLC6A2SLC6A3SLC6A4HTR1AHTR2C
SCHEMBL23926345 0.76 PREP (0.41)
SCHEMBL23964579 0.75 HTR2C (0.48) HTR2CHTR2B
SCHEMBL6377672 0.74 MAPT (0.44)
SCHEMBL23926371 0.74 APP (0.40)
SCHEMBL3164305 0.74 HIF1A (0.52) SLC6A2SLC6A3SLC6A4
SCHEMBL23964440 0.72 KLK7 (0.47)
SCHEMBL30118918 0.72 KLK7 (0.47)
SCHEMBL7147661 0.72 LMNA (0.42) SLC6A2SLC6A3
SCHEMBL23926358 0.71 PREP (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4168408-A1 COMPOUNDS FOR AND METHODS OF TREATING DISEASES Alterity Therapeutics Limited (AU) 2023-04-26 EP disclosed
WO-2021253091-A1 COMPOUNDS FOR AND METHODS OF TREATING DISEASES Alterity Therapeutics Limited (AU) 2021-12-23 WO disclosed
WO-2021253091-A1 COMPOUNDS FOR AND METHODS OF TREATING DISEASES Alterity Therapeutics Limited (AU) 2021-12-23 WO disclosed
US-11155547-B1 Compounds for and methods of treating diseases Alterity Therapeutics Limited (AU) 2021-10-26 US disclosed
US-11155547-B1 Compounds for and methods of treating diseases Alterity Therapeutics Limited (AU) 2021-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11155547-B1 Compounds for and methods of treating diseases HTT, SNCA, PARK7 SLC6A2 603/4885SLC6A3 182/4885SLC6A4 1724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.