Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.95 |
| ▸ | HPGD | P15428 | 5/20 | 0.95 |
| ▸ | TSHR | P16473 | 5/20 | 0.95 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.95 |
| ▸ | MEN1 | O00255 | 4/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.95 |
| ▸ | RECQL | P46063 | 3/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.95 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.95 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.95 |
| ▸ | MAPT | P10636 | 2/20 | 0.95 |
| ▸ | CASP1 | P29466 | 2/20 | 0.95 |
| ▸ | CASP7 | P55210 | 2/20 | 0.95 |
| ▸ | HTT | P42858 | 2/20 | 0.95 |
| ▸ | TTR | P02766 | 2/20 | 0.95 |
| ▸ | THRB | P10828 | 2/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bithionol SCHEMBL1158099 | 1.00 | HSD17B10 (0.95) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| Bithionol SCHEMBL29352300 | 0.98 | HSD17B10 (1.00) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| Bithionol SCHEMBL64385 | 0.98 | HSD17B10 (1.00) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| Bithionol SCHEMBL10392807 | 0.95 | HSD17B10 (0.95) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| Bithionol SCHEMBL29988662 | 0.95 | HSD17B10 (0.95) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL12655293 | 0.89 | HSD17B10 (0.83) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL14644985 | 0.86 | HSD17B10 (0.77) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL19197511 | 0.86 | MEN1 (0.77) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL9328645 | 0.84 | HSD17B10 (0.74) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| Bithionol SCHEMBL636174 | 0.84 | HSD17B10 (0.78) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3803402-B1 | ANTI-CANCER TREATMENT OF PRESELECTED SUBJECTS AND SCREENING METHODS TO IDENTIFY SUSCEPTIBLE SUBJECTS | TUDAG TU DRESDEN AG (DE) | 2023-04-26 | — | — | EP | disclosed |
| EP-3578981-B1 | ANTI-CANCER TREATMENT OF PRESELECTED SUBJECTS AND SCREENING METHODS TO IDENTIFY SUSCEPTIBLE SUBJECTS | TUDAG TU DRESDEN AG (DE) | 2021-10-27 | — | — | EP | disclosed |