Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.74 |
| ▸ | TSHR | P16473 | 7/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.74 |
| ▸ | HPGD | P15428 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | RECQL | P46063 | 3/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | CASP1 | P29466 | 2/20 | 0.74 |
| ▸ | CASP7 | P55210 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bithionol SCHEMBL29352300 | 0.86 | HSD17B10 (1.00) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| Bithionol SCHEMBL64385 | 0.86 | HSD17B10 (1.00) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| Bithionol SCHEMBL23926397 | 0.84 | HSD17B10 (0.95) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| Bithionol SCHEMBL29988662 | 0.84 | HSD17B10 (0.95) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| Bithionol SCHEMBL1158099 | 0.84 | HSD17B10 (0.95) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| Bithionol SCHEMBL10392807 | 0.84 | HSD17B10 (0.95) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| SCHEMBL12655293 | 0.79 | HSD17B10 (0.83) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| SCHEMBL14644985 | 0.76 | HSD17B10 (0.77) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| SCHEMBL19197511 | 0.76 | MEN1 (0.77) | HSD17B10TSHRCYP3A4HPGDALDH1A1 | |
| SCHEMBL9778278 | 0.75 | HSD17B10 (0.57) | HSD17B10TSHRCYP3A4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376318-B1 | Thermosensitive recording member | KAO CORP (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5091356-A | Comprising a substrate, a foamed dispersion layer of a self-emulsifiable resin, and a thermosensitive coloring layer containing a developer; stability; colorfastness; intensity | KAO CORPORATION (JP) | 1992-02-25 | — | — | US | disclosed |