Bithionol

Bithionol

SCHEMBL64385

Oc1c(Cl)cc(Cl)cc1Sc1cc(Cl)cc(Cl)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 1.00
ALDH1A1 P00352 5/20 1.00
HPGD P15428 5/20 1.00
TSHR P16473 5/20 1.00
CYP3A4 P08684 4/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
ALOX15 P16050 4/20 1.00
RECQL P46063 3/20 1.00
MAPK1 P28482 3/20 1.00
ALOX12 P18054 3/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
HIF1A Q16665 3/20 1.00
KDM4E B2RXH2 2/20 1.00
MAPT P10636 2/20 1.00
CASP1 P29466 2/20 1.00
CASP7 P55210 2/20 1.00
HTT P42858 2/20 1.00
TTR P02766 2/20 1.00
THRB P10828 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bithionol SCHEMBL29352300 1.00 HSD17B10 (1.00) HSD17B10ALDH1A1HPGDTSHRCYP3A4
Bithionol SCHEMBL1158099 0.98 HSD17B10 (0.95) HSD17B10ALDH1A1HPGDTSHRCYP3A4
Bithionol SCHEMBL10392807 0.98 HSD17B10 (0.95) HSD17B10ALDH1A1HPGDTSHRCYP3A4
Bithionol SCHEMBL23926397 0.98 HSD17B10 (0.95) HSD17B10ALDH1A1HPGDTSHRCYP3A4
Bithionol SCHEMBL29988662 0.98 HSD17B10 (0.95) HSD17B10ALDH1A1HPGDTSHRCYP3A4
SCHEMBL12655293 0.91 HSD17B10 (0.83) HSD17B10ALDH1A1HPGDTSHRCYP3A4
SCHEMBL14644985 0.88 HSD17B10 (0.77) HSD17B10ALDH1A1HPGDTSHRCYP3A4
SCHEMBL19197511 0.88 MEN1 (0.77) HSD17B10ALDH1A1HPGDTSHRCYP3A4
SCHEMBL9328645 0.86 HSD17B10 (0.74) HSD17B10ALDH1A1HPGDTSHRCYP3A4
Bithionol SCHEMBL636174 0.86 HSD17B10 (0.78) HSD17B10ALDH1A1HPGDTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6767 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
US-20260060936-A1 INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS TECHNION RES & DEV FOUNDATION (IL) 2026-03-05 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-4586826-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL In the Bowl Animal Health, Inc. (US) 2025-07-23 EP claimed
WO-2025129271-A1 LIPID DELIVERY VEHICLE THE UNIVERSITY OF QUEENSLAND (AU) 2025-06-26 WO claimed
US-20250185632-A1 CONTINUOUS IN-SITU THERAPEUTIC TREATMENT SYSTEM FOR FISH IN FRESHWATER, FROM SEAWATER Salmoclinic Spa (CL) 2025-06-12 US claimed
US-20250170082-A1 HPDL INHIBITORS AND USES THEREOF NEW YORK UNIVERSITY (US) 2025-05-29 US claimed
US-4636819-A SUPPORT, LEUCO DYE, DEVELOPER, WATER SOLUBLE RESIN RICOH COMPANY, LTD. (JP) 1987-01-13 US claimed
EP-0065053-B1 DIAZOTYPE MATERIAL TO BE DEVELOPED BY HEAT, WATER OR VAPOUR INTERNATIONAL DIAZO CHAPEL et Cie Société dite (FR) 1986-05-07 EP claimed
EP-0098151-B1 HEAT-SENSITIVE BLACK RECORDING ELEMENT MITA INDUSTRIAL CO. LTD. (JP) 1986-01-15 EP claimed
US-4502067-A DISPERSION OF LEUCO DYE, ORGANIC ACID AND SENSITIZER MITA INDUSTRIAL COMPANY LIMITED (JP) 1985-02-26 US claimed
US-4500897-A Heat-sensitive black recording element MITA INDUSTRIAL CO., LTD. (JP) 1985-02-19 US claimed
EP-0098728-A2 Heat-sensitive black recording material MITA INDUSTRIAL CO. LTD. (JP) 1984-01-18 EP claimed
EP-0098151-A2 Heat-sensitive black recording element MITA INDUSTRIAL CO. LTD. (JP) 1984-01-11 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4025399-A ELECTRICAL, RECORDING LAYER WITH A CONDUCTIVE AGENT, A LEUCO BASE AND A PHENOLIC RESIN CANON KABUSHIKI KAISHA (JA) 1977-05-24 US claimed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 US claimed