Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | GLA | P06280 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 6/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22130191 | 0.98 | MAPT (0.57) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL2222770 | 0.79 | ILK (0.60) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| Cyanide SCHEMBL22130193 | 0.76 | ILK (0.39) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL6854931 | 0.76 | MAPT (0.73) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL6854930 | 0.75 | MAPT (0.96) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL3194266 | 0.74 | MAPT (1.00) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL5535916 | 0.74 | MAPT (0.90) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL1995933 | 0.74 | MAPT (1.00) | MAPTKDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL30943961 | 0.74 | PIK3R1 (0.39) | MAPTKDM4EALDH1A1PKMHPGD | |
| SCHEMBL11749206 | 0.73 | MAPT (1.00) | MAPTKDM4EGLAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901139-A1 | NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF | Korea Institute of Science and Technology (KR) | 2021-10-27 | — | — | EP | disclosed |