Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263212 | 0.89 | IDO1 (0.50) | IDO1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL23961307 | 0.88 | IDO1 (0.45) | IDO1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9344493 | 0.82 | MEN1 (0.61) | IDO1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2030465 | 0.78 | IDO1 (0.50) | IDO1MEN1KMT2AHSD17B10CYP2A6 | |
| SCHEMBL19869137 | 0.78 | MAPT (0.42) | IDO1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9342625 | 0.76 | MEN1 (0.55) | IDO1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL835524 | 0.74 | MEN1 (0.53) | IDO1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL19869165 | 0.73 | MAOB (0.40) | IDO1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL623057 | 0.73 | — | — | |
| SCHEMBL23992950 | 0.72 | MEN1 (0.52) | IDO1MEN1KMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139281-B1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | UNIV HEIDELBERG (DE) | 2024-05-08 | — | — | EP | disclosed |
| CN-115974832-B | Disulfide bond-containing N-acetyl-L-cysteine derivative and preparation method and application thereof | 山东大学 | 2023-08-01 | — | — | CN | disclosed |
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-05-18 | — | — | US | disclosed |
| CN-115974832-A | Disulfide bond-containing N-acetyl-L-cysteine derivative and preparation method and application thereof | 山东大学 | 2023-04-18 | — | — | CN | disclosed |
| EP-3901135-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2021-10-27 | — | — | EP | disclosed |
| CN-107325058-B | Diaryl methylene disulfide compound and preparation method and application thereof | 苏州大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-107325058-A | Two fragrant methylene disulfide compounds and preparation method and application | 苏州大学 | 2017-11-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | TST, CBS, CTH | IDO1 1812/4885MEN1 2766/4885KMT2A 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.