Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20131980 | 0.83 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAOAMAOBNPC1 | |
| SCHEMBL13745985 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL29234008 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL36740 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL30360260 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL9452801 | 0.73 | POLB (0.38) | ALDH1A1SMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL20132283 | 0.73 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAOAMAOBRAB9A | |
| SCHEMBL28888981 | 0.72 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAOAMAOBNPC1 | |
| SCHEMBL9837809 | 0.71 | IDO1 (0.36) | IDO1AGXT | |
| SCHEMBL3116390 | 0.71 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |