SCHEMBL36740

SCHEMBL36740

CC(C)(C)[Si](C)(C)Oc1ccc(C=O)cc1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.50
TSHR P16473 1/20 0.50
FDPS P14324 1/20 0.44
AOX1 Q06278 1/20 0.42
TRIM24 O15164 1/20 0.42
HPGD P15428 1/20 0.42
ALDH5A1 P51649 1/20 0.42
ABAT P80404 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
TTR P02766 1/20 0.41
POLB P06746 1/20 0.40
DRD2 P14416 1/20 0.39
MAPT P10636 4/20 0.38
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A3 P47895 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30360260 1.00 ALDH1A1 (0.50) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL22428 0.92 ALDH1A1 (0.64) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL30504088 0.92 ALDH1A1 (0.64) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL498989 0.92 ALDH1A1 (0.64) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL1620788 0.88 ALDH1A1 (0.54) ALDH1A1TSHRFDPSHPGDTDP1
Piperidine SCHEMBL1082543 0.87 ALDH1A1 (0.40) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL29234008 0.87 ALDH1A1 (0.43) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL3116390 0.87 ALDH1A1 (0.43) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL23245 0.87 ALDH1A1 (0.43) ALDH1A1TSHRFDPSAOX1TRIM24
SCHEMBL3857336 0.87 ALDH1A1 (0.43) ALDH1A1TSHRFDPSAOX1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2716702-B1 METHOD FOR PRODUCING RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2020-11-04 EP claimed
US-9447255-B2 Method for producing rubber composition BRIDGESTONE CORPORATION (JP) 2016-09-20 US claimed
US-20140187693-A1 METHOD FOR PRODUCING RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
US-20250361387-A1 RUBBER COMPOSITION FOR TIRES AND TIRE BRIDGESTONE CORPORATION (JP) 2025-11-27 US disclosed
EP-4653495-A1 RUBBER COMPOSITION AND CROSSLINKED MATERIAL Kuraray Co., Ltd. (JP) 2025-11-26 EP disclosed
EP-3882046-B1 RUBBER COMPOSITION, VULCANIZED RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2025-07-30 EP disclosed
EP-4541848-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2025-04-23 EP disclosed
EP-3882045-B1 RUBBER COMPOSITION, VULCANIZED RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2025-03-26 EP disclosed
WO-2025028543-A1 TIRE RUBBER COMPOSITION, TIRE VULCANIZED RUBBER, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-02-06 WO disclosed
WO-2024154753-A1 RUBBER COMPOSITION AND CROSSLINKED MATERIAL 株式会社クラレ 2024-07-25 WO disclosed
EP-3725549-B1 TIRE FOR TWO-WHEELED VEHICLE BRIDGESTONE CORP (JP) 2024-02-07 EP disclosed
EP-0947498-A1 OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATES, AND PROCESS FOR PREPARING THE SAME CHISSO CORPORATION (JP) 1999-10-06 EP disclosed
US-5008471-A Process for the preparation of rooperol ROOPEROL (N.A.) (NL) 1991-04-16 US disclosed
EP-0206765-B1 PROCESS FOR PREPARATION OF ROOPEROL, HYPOXOSIDE AND DERIVATIVES THEREOF ROOPEROL (NA) NV (NL) 1991-03-06 EP disclosed
US-4959391-A LIPOXYGENASE INHIBITORS, LEUKOTRIENE DISEASES GRUENENTHAL GMBH (DE) 1990-09-25 US disclosed
US-4956502-A Process for the preparation of rooperol derivative ROOPEROL (N.A.) NV (AN) 1990-09-11 US disclosed
EP-0202529-B1 PHENOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF THESE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS Grünenthal GmbH (DE) 1989-12-13 EP disclosed
US-4760087-A 5-lipoxygenase inhibitor GRUENENTHAL GMBH (DE) 1988-07-26 US disclosed
EP-0206765-A2 Process for preparation of rooperol, hypoxoside and derivatives thereof ROOPEROL (NA) NV (NL) 1986-12-30 EP disclosed
EP-0202529-A2 Phenol derivatives, pharmaceutical compositions containing them and processes for the preparation of these compounds and pharmaceutical compositions Grünenthal GmbH (DE) 1986-11-26 EP disclosed