Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927534 | 0.89 | MT-CO2 (0.36) | MAPTALDH1A1SMN1; SMN2LMNAHCAR2 | |
| SCHEMBL23927537 | 0.89 | APP (0.32) | HCAR2 | |
| SCHEMBL23927535 | 0.88 | MAPT (0.34) | MAPTALDH1A1HTT | |
| SCHEMBL23927538 | 0.85 | KMT2A (0.33) | MAPTALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL23927533 | 0.83 | MAPT (0.32) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL14740849 | 0.72 | AAK1 (0.39) | AAK1 | |
| SCHEMBL14740772 | 0.72 | HCAR2 (0.44) | ALDH1A1KDM4EHPGDHCAR2 | |
| SCHEMBL2138096 | 0.69 | RAB9A (0.45) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL7151045 | 0.69 | CNR1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL17336825 | 0.68 | RXFP1 (0.35) | MAPTALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751095-B1 | NOVEL BENZODIAZEPINONES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR FUNCTIONS AND NEUROLOGICAL USES THEREOF | SANFORD BURNHAM MED RES INST (US) | 2021-10-27 | — | — | EP | disclosed |