Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927703 | 0.89 | ROCK2 (0.38) | EGFRROCK2ROCK1 | |
| SCHEMBL23927614 | 0.88 | EGFR (0.37) | EGFRROCK2MAPTALDH1A1 | |
| SCHEMBL28408118 | 0.81 | ICAM1 (0.40) | ROCK2ICAM1SELEROCK1MYLK4 | |
| SCHEMBL23501200 | 0.80 | ROCK2 (0.52) | ROCK2ICAM1SELEROCK1MYLK4 | |
| SCHEMBL30744167 | 0.80 | ROCK2 (0.52) | ROCK2ICAM1SELEROCK1MYLK4 | |
| SCHEMBL23501202 | 0.80 | ROCK2 (0.52) | ROCK2ICAM1SELEROCK1MYLK4 | |
| SCHEMBL23927687 | 0.79 | ROCK2 (0.35) | ROCK2ICAM1SELEROCK1MYLK4 | |
| SCHEMBL23927681 | 0.79 | ROCK2 (0.35) | ROCK2ICAM1SELEROCK1MYLK4 | |
| SCHEMBL23927612 | 0.77 | ROCK2 (0.41) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23522334 | 0.76 | RAB9A (0.42) | ROCK2ICAM1SELEVCAM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332726-A1 | NITROXIDE DERIVATIVE OF ROCK KINASE INHIBITOR | VIVAVISION (SHANGHAI) LTD (CN) | 2022-10-20 | — | — | US | disclosed |
| EP-3901156-A1 | NITROOXYDERIVATIVE OF ROCK KINASE INHIBITOR | Vivavision (Shanghai) Ltd (CN) | 2021-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332726-A1 | NITROXIDE DERIVATIVE OF ROCK KINASE INHIBITOR | ROCK1, NOS1, ROCK2 | EGFR 3359/4885ROCK2 3/4885ICAM1 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.