Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928122 | 0.82 | CNR1 (0.49) | NPC1RAB9ASMN1; SMN2CNR1KDM4E | |
| SCHEMBL4511148 | 0.82 | KDM4E (0.52) | NPC1RAB9ASMN1; SMN2KDM4EF13A1 | |
| SCHEMBL23291226 | 0.81 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2CNR1FFAR1 | |
| SCHEMBL23928193 | 0.81 | HRH3 (0.50) | NPC1RAB9ACNR1FFAR1KDM4E | |
| SCHEMBL28255137 | 0.80 | CNR1 (0.46) | NPC1RAB9ASMN1; SMN2CNR1FFAR1 | |
| SCHEMBL4584283 | 0.80 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2CNR1KDM4E | |
| SCHEMBL23291264 | 0.79 | NAMPT (0.57) | NPC1RAB9ASMN1; SMN2KMT2AGLA | |
| SCHEMBL23135379 | 0.78 | ADRA2A (0.45) | KDM4EF13A1KMT2AMAPTALDH1A1 | |
| SCHEMBL6184546 | 0.78 | CNR1 (0.49) | NPC1RAB9ASMN1; SMN2CNR1KMT2A | |
| SCHEMBL20541797 | 0.77 | GRIN1 (0.56) | SMN1; SMN2KDM4EKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845751-B2 | Triazolotriazine derivatives as A2A receptor antagonists | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2023-12-19 | — | — | US | disclosed |
| US-20210332055-A1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11845751-B2 | Triazolotriazine derivatives as A2A receptor antagonists | ADORA2A, ADORA1, ADORA3 | NPC1 1520/4885RAB9A 2869/4885SMN1; SMN2 4178/4885 |
| US-20210332055-A1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | ADORA2A, ADORA1, ADORA3 | NPC1 1520/4885RAB9A 2869/4885SMN1; SMN2 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.