Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 4/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167751 | 0.81 | NAMPT (0.58) | CNR1MAPTKMT2ALMNA | |
| SCHEMBL23928207 | 0.78 | NPC1 (0.47) | CNR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23928122 | 0.77 | CNR1 (0.49) | CNR1MAPTKMT2AALDH1A1FPR2 | |
| SCHEMBL4511148 | 0.77 | KDM4E (0.52) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16620097 | 0.76 | NPC1 (0.56) | CNR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19876843 | 0.75 | CNR1 (0.50) | CNR1MAPTMEN1KMT2AFPR2 | |
| SCHEMBL4584283 | 0.75 | NPC1 (0.64) | CNR1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL19066251 | 0.74 | KDM4E (0.64) | CNR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14612489 | 0.73 | RAB9A (0.77) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4648147 | 0.73 | POLB (0.52) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494667-A1 | IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | Pfizer Japan Inc. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086390-A1 | IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER JAPAN INC. (JP) | 2003-10-23 | — | — | WO | disclosed |