SCHEMBL23928357

SCHEMBL23928357

Cc1ccc(-c2cc(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c(C)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
RXRB P28702 5/20 0.40
RXRA P19793 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 2/20 0.37
RXRG P48443 2/20 0.36
ABCG2 Q9UNQ0 3/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29988782 1.00 MAPT (0.41) MAPTKDM4EGAARXRBRXRA
SCHEMBL23959658 1.00 MAPT (0.41) MAPTKDM4EGAARXRBRXRA
SCHEMBL29988331 0.97 RXRB (0.44) MAPTKDM4EGAARXRBRXRA
SCHEMBL23959723 0.97 RXRB (0.40) MAPTKDM4EGAARXRBRXRA
SCHEMBL32664312 0.97 RXRB (0.40) MAPTKDM4EGAARXRBRXRA
SCHEMBL23928362 0.97 RXRB (0.44) MAPTKDM4EGAARXRBRXRA
SCHEMBL23959694 0.94 KDM4E (0.37) MAPTKDM4EGAARXRBRXRA
SCHEMBL23959677 0.93 MAPT (0.46) MAPTKDM4EGAARXRBRXRA
SCHEMBL23959698 0.93 KDM4E (0.38) MAPTKDM4EGAARXRBRXRA
SCHEMBL23959754 0.88 RXRB (0.39) MAPTKDM4EGAARXRBRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260040760-A1 Hole-Transport Layer Material, Electron-Blocking Layer Material, Electron-Transport Layer Material, Hole-Blocking Layer Material, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2026-02-05 US disclosed
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-10-28 US disclosed
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260040760-A1 Hole-Transport Layer Material, Electron-Blocking Layer Material, Electron-Transport Layer Material, Hole-Blocking Layer Material, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, And Lighting Device CTNNB1, AXIN2, SLC9A2 MAPT 1943/4885KDM4E 3094/4885GAA 2103/4885
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SPIN3, SLC39A3, SKIC3 MAPT 1456/4885KDM4E 4238/4885GAA 4247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.