Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.75 |
| ▸ | CA1 | P00915 | 5/20 | 0.75 |
| ▸ | CA2 | P00918 | 5/20 | 0.75 |
| ▸ | CA9 | Q16790 | 5/20 | 0.75 |
| ▸ | AURKA | O14965 | 5/20 | 0.71 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597826 | 0.90 | CA12 (0.69) | CA12CA1CA2CA9AURKA | |
| SCHEMBL5947916 | 0.90 | AURKA (0.74) | CA12CA1CA2CA9AURKA | |
| SCHEMBL23928515 | 0.85 | AURKA (0.79) | CA12CA1CA2CA9AURKA | |
| SCHEMBL6259170 | 0.85 | CA12 (0.75) | CA12CA1CA2CA9AURKA | |
| SCHEMBL23928535 | 0.84 | AURKA (0.78) | CA12CA1CA2CA9AURKA | |
| SCHEMBL23928476 | 0.84 | MAPT (0.75) | CA12CA1CA2CA9AURKA | |
| SCHEMBL23928478 | 0.84 | ALDH1A1 (0.78) | CA12CA1CA2CA9AURKA | |
| SCHEMBL22095633 | 0.83 | AURKA (1.00) | AURKAPPARGMEN1KMT2AMAPT | |
| SCHEMBL16597850 | 0.83 | PPARG (0.57) | CA12CA1CA2CA9AURKA | |
| SCHEMBL23928621 | 0.82 | AURKA (0.73) | CA12CA1CA2CA9AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548875-B2 | Inhibitor compounds for male contraception | UNIVERSITY OF WASHINGTON (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | ALDH1A1, ALDH3A1, ALDH16A1 | CA12 4702/4885CA1 3645/4885CA2 4424/4885 |
| US-11548875-B2 | Inhibitor compounds for male contraception | ALDH1A1, ALDH3A1, ALDH16A1 | CA12 4702/4885CA1 3645/4885CA2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.