Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 7/20 | 0.64 |
| ▸ | CDK2 | P24941 | 3/20 | 0.63 |
| ▸ | CDK1 | P06493 | 1/20 | 0.63 |
| ▸ | CDK4 | P11802 | 1/20 | 0.63 |
| ▸ | CDK7 | P50613 | 1/20 | 0.63 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22095227 | 0.93 | MAPT (0.88) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL22095118 | 0.92 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22095142 | 0.92 | MAPT (0.84) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22095578 | 0.92 | MAPT (0.84) | MAPTKMT2AMEN1RAB9ALMNA | |
| SCHEMBL22094960 | 0.91 | MAPT (0.76) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22095615 | 0.90 | MAPT (0.78) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL22095114 | 0.88 | MAPT (0.78) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL23928538 | 0.87 | MAPT (0.77) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22095047 | 0.87 | LMNA (0.85) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL22095215 | 0.87 | MEN1 (0.69) | MAPTKMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548875-B2 | Inhibitor compounds for male contraception | UNIVERSITY OF WASHINGTON (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | ALDH1A1, ALDH3A1, ALDH16A1 | MAPT 4083/4885KMT2A 1384/4885MEN1 3040/4885 |
| US-11548875-B2 | Inhibitor compounds for male contraception | ALDH1A1, ALDH3A1, ALDH16A1 | MAPT 4083/4885KMT2A 1384/4885MEN1 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.