Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840936 | 0.83 | ALDH1A1 (0.64) | DCTPP1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL22095026 | 0.82 | MAPT (0.55) | DCTPP1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL2463380 | 0.81 | DCTPP1 (0.67) | DCTPP1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL23928687 | 0.81 | DCTPP1 (0.66) | DCTPP1KMT2AMAPTMAPK1PAX8 | |
| SCHEMBL2483606 | 0.79 | ALDH1A1 (0.69) | DCTPP1KMT2AMAPTPAX8ALDH1A1 | |
| SCHEMBL6708638 | 0.77 | ALDH1A1 (0.77) | DCTPP1KMT2AMAPTMAPK1PAX8 | |
| SCHEMBL30125018 | 0.76 | MAPT (0.61) | DCTPP1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL7809558 | 0.76 | MAPT (0.67) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL7937307 | 0.74 | ALDH1A1 (0.65) | DCTPP1KMT2AMAPTMAPK1PAX8 | |
| SCHEMBL24711152 | 0.74 | MAPT (0.77) | KMT2AMAPTMAPK1PAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548875-B2 | Inhibitor compounds for male contraception | UNIVERSITY OF WASHINGTON (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | ALDH1A1, ALDH3A1, ALDH16A1 | DCTPP1 1257/4885KMT2A 1384/4885MAPT 4083/4885 |
| US-11548875-B2 | Inhibitor compounds for male contraception | ALDH1A1, ALDH3A1, ALDH16A1 | DCTPP1 1257/4885KMT2A 1384/4885MAPT 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.