SCHEMBL23928757

SCHEMBL23928757

[CH2]CSSCCOC(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 8/20 0.46
SLC6A11 P48066 4/20 0.42
SLC6A1 P30531 2/20 0.42
KCNH2 Q12809 1/20 0.40
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
KMT2A Q03164 1/20 0.37
SLC6A12 P48065 1/20 0.37
SLC6A13 Q9NSD5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27177312 1.00 KIF11 (0.46) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL27177314 0.88 KIF11 (0.52) KIF11SLC6A1
SCHEMBL9537662 0.87 KIF11 (0.47) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL27177311 0.86 KIF11 (0.46) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL7165376 0.86 KIF11 (0.46) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL2985182 0.82 KIF11 (0.49) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL13658487 0.82 KIF11 (0.47) KIF11SLC6A11SLC6A1KCNH2
SCHEMBL16021678 0.81 KIF11 (0.46) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL30770594 0.80 KIF11 (0.43) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL3997667 0.80 KIF11 (0.48) KIF11SLC6A11SLC6A1KCNH2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4341270-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES Olix US, Inc. (US) 2024-03-27 EP claimed
EP-4341270-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES Olix US, Inc. (US) 2024-03-27 EP disclosed
EP-4143316-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2023-03-08 EP disclosed
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2022-06-14 US disclosed
WO-2021220053-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-11-04 WO disclosed
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN KIF11 1884/4885SLC6A11 4742/4885SLC6A1 4609/4885
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN KIF11 1884/4885SLC6A11 4742/4885SLC6A1 4609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.