SCHEMBL2985182

SCHEMBL2985182

[CH2]CCOC(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.49
SLC6A11 P48066 4/20 0.47
SLC6A1 P30531 2/20 0.47
KCNH2 Q12809 1/20 0.46
CA4 P22748 1/20 0.42
LTA4H P09960 2/20 0.42
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC6A12 P48065 1/20 0.41
SLC6A13 Q9NSD5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3997667 0.90 KIF11 (0.48) KIF11SLC6A11SLC6A1KCNH2CA4
SCHEMBL28353747 0.88 KIF11 (0.46) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL29194837 0.88 KIF11 (0.46) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL29194795 0.88 KIF11 (0.46) KIF11SLC6A11SLC6A1KCNH2MEN1
SCHEMBL18803715 0.86 KIF11 (0.52) KIF11SLC6A11SLC6A1KCNH2CA4
SCHEMBL14879264 0.86 KIF11 (0.52) KIF11SLC6A11SLC6A1KCNH2CA4
SCHEMBL3996218 0.86 KIF11 (0.49) KIF11SLC6A11SLC6A1KCNH2CA4
SCHEMBL27989498 0.86 KIF11 (0.63) KIF11SLC6A1
SCHEMBL10022830 0.83 KIF11 (0.49) KIF11SLC6A11SLC6A1KCNH2CA4
SCHEMBL2490410 0.83 SLC6A11 (0.50) KIF11SLC6A11SLC6A1KCNH2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117916374-A Oligonucleotide-based delivery vehicles for oligonucleotide agents and methods of use thereof 中美瑞康核酸技术(南通)研究院有限公司 2024-04-19 CN claimed
US-20030129589-A1 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. 2003-07-10 US claimed
US-20020042112-A1 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. 2002-04-11 US claimed
EP-0954612-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1999-11-10 EP claimed
WO-1998020166-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1998-05-14 WO claimed
CN-117916374-A Oligonucleotide-based delivery vehicles for oligonucleotide agents and methods of use thereof 中美瑞康核酸技术(南通)研究院有限公司 2024-04-19 CN disclosed
EP-1457496-B1 High density immobilization of nucleic acids SEQUENOM INC (US) 2014-01-15 EP disclosed
US-7771929-B2 Tag library compounds, compositions, kits and methods of use MONOGRAM BIOSCIENCES, INC. (US) 2010-08-10 US disclosed
EP-1296143-B1 Mass spectrometric detection of polypeptides SEQUENOM INC (US) 2009-06-03 EP disclosed
WO-2009049007-A2 COMPOSITIONS, METHODS AND SYSTEMS FOR RAPID IDENTIFICATION OF PATHOGENIC NUCLEIC ACIDS MAGELLAN BIOSCIENCES, INC. (US) 2009-04-16 WO disclosed
US-7501251-B2 DNA diagnostics based on mass spectrometry SEQUENOM, INC. (US) 2009-03-10 US disclosed
US-20090023150-A1 DNA Diagnostics Based on Mass Spectrometry SEQUENOM, INC. (US) 2009-01-22 US disclosed
US-6322970-B1 DIAGNOSING GENETIC OR CHROMOSOMAL DISORDERS; IN VITRO TRANSCRIPTION AND TRANSLATION; SEQUENCE DETERMINATION SEQUENOM, INC. 2001-11-27 US disclosed
WO-2001083502-A1 TAG LIBRARY COMPOUNDS, COMPOSITIONS, KITS AND METHODS OF USE ACLARA BIOSCIENCES, INC. (US) 2001-11-08 WO disclosed
EP-1010008-A2 MASS SPECTROMETRIC DETECTION OF POLYPEPTIDES SEQUENOM, INC. (US) 2000-06-21 EP disclosed
EP-0954612-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1999-11-10 EP disclosed
EP-0937096-A2 HIGH DENSITY IMMOBILIZATION OF NUCLEIC ACIDS SEQUENOM, INC. (US) 1999-08-25 EP disclosed
WO-1999012040-A2 MASS SPECTROMETRIC DETECTION OF POLYPEPTIDES SEQUENOM, INC. (US) 1999-03-11 WO disclosed
WO-1998020166-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1998-05-14 WO disclosed
WO-1998020020-A2 HIGH DENSITY IMMOBILIZATION OF NUCLEIC ACIDS SEQUENOM, INC. (US) 1998-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042112-A1 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY DNA2, DDB1, DNMT3A KIF11 1143/4885SLC6A11 3886/4885SLC6A1 4252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.