Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13658487 | 0.90 | KIF11 (0.47) | KIF11KCNH2SLC6A11SLC6A1 | |
| SCHEMBL15471570 | 0.85 | KIF11 (0.43) | KIF11KCNH2SLC6A11SLC6A1MAPT | |
| SCHEMBL12582832 | 0.84 | KIF11 (0.42) | KIF11KCNH2SLC6A11SLC6A1MEN1 | |
| SCHEMBL8327519 | 0.84 | KIF11 (0.42) | KIF11KCNH2SLC6A11SLC6A1MEN1 | |
| SCHEMBL14277882 | 0.83 | SLC6A11 (0.41) | KIF11KCNH2SLC6A11SLC6A1SMN1; SMN2 | |
| SCHEMBL2288433 | 0.82 | SLC6A11 (0.43) | KIF11KCNH2SLC6A11SLC6A1MEN1 | |
| SCHEMBL28882285 | 0.82 | KIF11 (0.40) | KIF11KCNH2SLC6A11SLC6A1ALDH1A1 | |
| SCHEMBL16197752 | 0.82 | KIF11 (0.50) | KIF11KCNH2SLC6A11SLC6A1MEN1 | |
| SCHEMBL28353344 | 0.81 | RAB9A (0.43) | KIF11KCNH2SLC6A11SLC6A1ALDH1A1 | |
| SCHEMBL28353402 | 0.81 | KIF11 (0.40) | KIF11KCNH2SLC6A11SLC6A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160333045-A1 | Preparation of Oligo Conjugates | Emerald Therapeutics, Inc. | 2016-11-17 | — | — | US | disclosed |
| US-9289502-B2 | Preparation of oligo conjugates | Emerald Therapeutics, Inc. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140256911-A1 | PREPARATION OF OLIGO CONJUGATES | Emerald Therapeutics, Inc. | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160333045-A1 | Preparation of Oligo Conjugates | OSTC, PCBP1, PAICS | KIF11 1102/4885KCNH2 4810/4885SLC6A11 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.