Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.91 |
| ▸ | CA9 | Q16790 | 9/20 | 0.91 |
| ▸ | CA1 | P00915 | 6/20 | 0.91 |
| ▸ | CA3 | P07451 | 5/20 | 0.91 |
| ▸ | CA4 | P22748 | 5/20 | 0.91 |
| ▸ | CA5A | P35218 | 5/20 | 0.91 |
| ▸ | CA7 | P43166 | 5/20 | 0.91 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.91 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.91 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.91 |
| ▸ | CA6 | P23280 | 4/20 | 0.91 |
| ▸ | CA2 | P00918 | 3/20 | 0.91 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.91 |
| ▸ | LMNA | P02545 | 3/20 | 0.91 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.91 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL28031527 | 0.98 | CA12 (0.87) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL29385611 | 0.95 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL28886137 | 0.95 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL621751 | 0.95 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL3441294 | 0.95 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL6252 | 0.95 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL1038138 | 0.95 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL1193624 | 0.93 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL8144767 | 0.93 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL382038 | 0.93 | CA12 (0.95) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069885-A | Preparation method and application of novel copolymer material based on coumarin and rhodamine | 大连大学 | 2023-11-17 | — | — | CN | claimed |
| CN-114790257-B | Polymer white light material based on coumarin and rare earth complex and preparation method thereof | 大连大学 | 2023-06-23 | — | — | CN | claimed |
| CN-110204535-B | Coumarin hydrazine hydrate fluorescent probe and preparation method thereof | 福州大学 | 2022-09-13 | — | — | CN | claimed |
| CN-114790257-A | Novel polymer white light material based on coumarin and rare earth complex and preparation method thereof | 大连大学 | 2022-07-26 | — | — | CN | claimed |
| CN-113402655-B | Polymer universal fluorescence platform for FRET fluorescent probe donor and application thereof | 大连大学 | 2022-05-10 | — | — | CN | claimed |
| WO-2015041729-A2 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF α-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2015-03-26 | — | — | WO | claimed |
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-12-04 | — | — | US | claimed |
| CN-117069885-A | Preparation method and application of novel copolymer material based on coumarin and rhodamine | 大连大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-114790257-B | Polymer white light material based on coumarin and rare earth complex and preparation method thereof | 大连大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-110204535-B | Coumarin hydrazine hydrate fluorescent probe and preparation method thereof | 福州大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-110204535-B | Coumarin hydrazine hydrate fluorescent probe and preparation method thereof | 福州大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-114790257-A | Novel polymer white light material based on coumarin and rare earth complex and preparation method thereof | 大连大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-113402655-B | Polymer universal fluorescence platform for FRET fluorescent probe donor and application thereof | 大连大学 | 2022-05-10 | — | — | CN | disclosed |
| US-20210356472-A1 | METHODS AND COMPOSITIONS FOR DETECTION AND VISUALIZATION OF OXIDATIVE STRESS-INDUCED CARBONYLATION IN CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2021-11-18 | — | — | US | disclosed |
| CN-113402655-A | Polymer universal fluorescence platform for FRET fluorescent probe donor and application thereof | 大连大学 | 2021-09-17 | — | — | CN | disclosed |
| US-10071990-B2 | Site-specific orthogonal labeling of the carboxy terminus of α-tubulin in live cells | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-09-11 | — | — | US | disclosed |
| WO-2015041729-A2 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF α-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2015-03-26 | — | — | WO | disclosed |
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-12-04 | — | — | US | disclosed |
| WO-2003101755-A1 | AUTHENTICATION MEANS | UCB, S.A. (BE) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | TUBB, TUBA1C, TUBB1 | CA12 3783/4885CA9 4428/4885CA1 3082/4885 |
| US-10071990-B2 | Site-specific orthogonal labeling of the carboxy terminus of α-tubulin in live cells | TUBB, TUBA1C, TUBB1 | CA12 3809/4885CA9 4448/4885CA1 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.