SCHEMBL2392922

SCHEMBL2392922

C[C@H](N)C(=O)N[C@@H](C)C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.54
MEN1 O00255 9/20 0.54
GAA P10253 2/20 0.54
LMNA P02545 3/20 0.53
MAPT P10636 7/20 0.51
ALDH1A1 P00352 3/20 0.51
NPSR1 Q6W5P4 2/20 0.51
MYOC Q99972 1/20 0.51
HTR1E P28566 1/20 0.50
S1PR3 Q99500 1/20 0.50
NPC1 O15118 2/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPK1 P28482 1/20 0.49
POLB P06746 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
TGM2 P21980 1/20 0.48
NAMPT P43490 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1651305 0.99 KMT2A (0.53) KMT2AMEN1GAALMNAMAPT
Hydrochloric Acid SCHEMBL11567226 0.99 KMT2A (0.53) KMT2AMEN1GAALMNAMAPT
SCHEMBL987822 0.91 KMT2A (0.61) KMT2AMEN1GAALMNAMAPT
SCHEMBL10914836 0.91 KMT2A (0.61) KMT2AMEN1GAALMNAMAPT
SCHEMBL9259881 0.91 KMT2A (0.61) KMT2AMEN1GAALMNAMAPT
SCHEMBL29629276 0.90 MMP9 (0.47) KMT2AMEN1GAALMNAMAPT
Hydrochloric Acid SCHEMBL1895198 0.89 KMT2A (0.59) KMT2AMEN1GAALMNAMAPT
SCHEMBL2681740 0.87 KMT2A (0.56) KMT2AMEN1GAALMNAMAPT
SCHEMBL3692748 0.84 ABCG2 (0.58) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL6820632 0.83 PDF (0.56) KMT2AMEN1GAALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119073578-A Preparation method and application of water lily extract with anti-aging effect 上海应用技术大学 2024-12-06 CN disclosed
CN-112137937-B Active composition with skin aging delaying function and application thereof 楚香(上海)生物科技有限公司 2023-05-02 CN disclosed
CN-107105707-B Proline tolerant tripeptidylpeptidases and uses thereof 杜邦营养生物科学有限公司 2022-07-22 CN disclosed
CN-114573682-A Elastin peptide and preparation method thereof 华南理工大学 2022-06-03 CN disclosed
EP-3914614-A1 METHODS OF PRODUCING AND USING RECOMBINANT ALPHA 1-ANTITRYPSIN (AAT) AND COMPOSITIONS THEREOF Excellgene SA (CH) 2021-12-01 EP disclosed
EP-3694570-A1 ELASTIN REDUCTION ALLOWING RECELLULARIZATION OF CARTILAGE IMPLANTS Trauma Care Consult Traumatologische Forschung Gemeinnützige Gesellschaft mbH (AT) 2020-08-19 EP disclosed
WO-2020152653-A1 METHODS OF PRODUCING AND USING RECOMBINANT ALPHA 1-ANTITRYPSIN (AAT) AND COMPOSITIONS THEREOF EXCELLGENE SA (CH) 2020-07-30 WO disclosed
EP-3676329-A1 BIODEGRADABLE POLYESTER ARTICLE COMPRISING ENZYMES Carbiolice (FR) 2020-07-08 EP disclosed
WO-2019073079-A1 ELASTIN REDUCTION ALLOWING RECELLULARIZATION OF CARTILAGE IMPLANTS NUERNBERGER SYLVIA (AT) 2019-04-18 WO disclosed
WO-2019043134-A1 BIODEGRADABLE POLYESTER ARTICLE COMPRISING ENZYMES CARBIOLICE (FR) 2019-03-07 WO disclosed
EP-1317555-B1 RAT CATHEPSIN, DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE, INHIBITORS AND ITS USES PROZYMEX AS (DK) 2007-11-14 EP disclosed
US-20040043469-A1 Dipeptidyl peptidase i crystal structure and its uses PROZYMEX A/S (DK) 2004-03-04 US disclosed
EP-1317555-A1 RAT CATHEPSIN, DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE, INHIBITORS AND ITS USES Prozymex A/S (DK) 2003-06-11 EP disclosed
WO-2002020804-A1 RAT CATHEPSIN, DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE, INHIBITORS AND ITS USES PROZYMEX A/S (DK) 2002-03-14 WO disclosed
EP-1042287-A1 INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA Aventis Pharma Deutschland GmbH (DE) 2000-10-11 EP disclosed
US-6127144-A PRODUCING HETEROLOGOUS PROTEINS BY INCUBATING STREPTOMYCES CELL TRANSFORMED WITH NUCLEIC ACID EXPRESSION CONSTRUCT IN PRESENCE OF PEPTIDE-SUSBSTITUTED CHLOROMETHYLKETONE AMINOPEPTIDASE INHIBITOR HAVING DEFINED STRUCTURE CANGENE CORPORATION (CA) 2000-10-03 US disclosed
WO-1999033800-A1 INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 1999-07-08 WO disclosed
EP-0758341-A1 FACTOR Xa INHIBITORS SELECTIDE CORPORATION (US) 1997-02-19 EP disclosed
EP-0731841-A1 PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS Cangene Corporation (CA) 1996-09-18 EP disclosed
WO-1995017512-A2 PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS CANGENE CORPORATION (CA) 1995-06-29 WO disclosed