Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MYOC | Q99972 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651305 | 0.91 | KMT2A (0.53) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL2392922 | 0.90 | KMT2A (0.54) | MEN1KMT2ALMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL11567226 | 0.88 | KMT2A (0.53) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL9259881 | 0.84 | KMT2A (0.61) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL987822 | 0.84 | KMT2A (0.61) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL10914836 | 0.84 | KMT2A (0.61) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL1033030 | 0.83 | MMP9 (0.42) | MMP9MEN1KMT2ALMNAGAA | |
| Hydrochloric Acid SCHEMBL1895198 | 0.82 | KMT2A (0.59) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL1088019 | 0.80 | MMP9 (0.41) | MMP9MEN1KMT2ALMNAGAA | |
| SCHEMBL28183373 | 0.79 | MMP2 (0.55) | MMP9MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112007033-B | Pabocillin for preparing medicine composition for treating patient suffering from diseases and inhibiting phosphatidylinositol 3-kinase activity and use | 长庚大学 | 2022-06-24 | — | — | CN | disclosed |