Sugi Predict

Sugi Predict / Compounds / SCHEMBL20897239

SCHEMBL20897239

SCHEMBL20897239

CCOC(=O)c1cc(CCc2ccc(F)cc2)n[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALPL P05186 2/20 0.47
▸ MAPT P10636 6/20 0.46
▸ NPC1 O15118 3/20 0.46
▸ RAB9A P51151 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ HPGDS O60760 2/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ DAO P14920 1/20 0.43
▸ TP53 P04637 2/20 0.42
▸ CASP3 P42574 1/20 0.42
▸ SENP8 Q96LD8 1/20 0.42
▸ SENP7 Q9BQF6 1/20 0.42
▸ SENP6 Q9GZR1 1/20 0.42
▸ MEN1 O00255 2/20 0.41
▸ POLB P06746 2/20 0.41
▸ TRPM8 Q7Z2W7 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24622058 0.88 DAO (0.46) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL23929236 0.87 HPGDS (0.57) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL30307859 0.87 HPGDS (0.39) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL24622046 0.86 ALPL (0.44) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL16763424 0.86 ALPL (0.55) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL20897252 0.81 CA12 (0.55) ALPLDAOTP53
SCHEMBL1359 0.81 ALPL (0.52) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL20897259 0.79 ALPL (0.53) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL15273871 0.79 ALPL (0.40) ALPLMAPTNPC1RAB9AKMT2A
SCHEMBL7008825 0.78 ALPL (0.50) ALPLMAPTNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521410-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2026-01-13 — — US disclosed
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2024-06-06 — — US disclosed
CN-111479806-B D-amino acid oxidase inhibitors and therapeutic uses thereof 心悦生医股份有限公司 2024-01-30 — — CN disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 — — US disclosed
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-09-12 — — US disclosed
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-09-12 — — US disclosed
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-09-12 — — US disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 — — CN disclosed
EP-4139275-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF Syneurx International (Taiwan) Corp. (TW) 2023-03-01 — — EP disclosed
US-20220218730-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-07-14 — — US disclosed
US-20200331894-A1 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2020-10-22 — — US disclosed
US-20200331894-A1 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2020-10-22 — — US disclosed
CN-111479806-A D-amino acid oxidase inhibitors and therapeutic uses thereof 心悦生医股份有限公司 2020-07-31 — — CN disclosed
WO-2019076329-A9 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF TSAI GUOCHUAN EMIL (CN) 2019-08-15 — — WO disclosed
US-10336724-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2019-07-02 — — US disclosed
US-10336724-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2019-07-02 — — US disclosed
WO-2019076329-A1 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF TSAI GUOCHUAN EMIL (CN) 2019-04-25 — — WO disclosed
US-20190112289-A1 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF TSAI, GUOCHUAN EMIL (US) 2019-04-18 — — US disclosed
US-20190112289-A1 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF TSAI, GUOCHUAN EMIL (US) 2019-04-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331894-A1 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF DAO, DDO, DDC ALPL 470/4885MAPT 2705/4885NPC1 3014/4885
US-20220218730-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF HRH4, OR10J3, CYP3A5 ALPL 3398/4885MAPT 2751/4885NPC1 198/4885
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof DAO, DDO, DDC ALPL 470/4885MAPT 2705/4885NPC1 3014/4885
US-10336724-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof DAO, DDO, DDC ALPL 470/4885MAPT 2705/4885NPC1 3014/4885
US-20190112289-A1 D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF DAO, DDO, DDC ALPL 469/4885MAPT 2728/4885NPC1 3046/4885
US-11793823-B2 Compounds and pharmaceutical uses thereof HRH4, OR10J3, CYP3A5 ALPL 3398/4885MAPT 2751/4885NPC1 198/4885
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF HRH4, OR10J3, CYP3A5 ALPL 3398/4885MAPT 2751/4885NPC1 198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.