SCHEMBL23929236

SCHEMBL23929236

CCOC(=O)c1cc(CCc2ccccc2)n[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 2/20 0.57
MAPT P10636 7/20 0.49
TP53 P04637 1/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
ALPL P05186 2/20 0.49
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
KMT2A Q03164 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16763424 0.89 ALPL (0.55) HPGDSMAPTTP53CASP3SENP8
SCHEMBL16112173 0.88 HPGDS (0.59) HPGDSMAPTTP53CASP3SENP8
SCHEMBL20897239 0.87 ALPL (0.47) HPGDSMAPTTP53CASP3SENP8
SCHEMBL20660941 0.86 HPGDS (0.52) HPGDSMAPTTP53CASP3SENP8
SCHEMBL20897259 0.86 ALPL (0.53) HPGDSMAPTTP53CASP3SENP8
SCHEMBL20897256 0.86 GAA (0.57) HPGDSMAPTALPLNPC1RAB9A
SCHEMBL17288834 0.84 HPGDS (0.55) HPGDSMAPTTP53CASP3SENP8
SCHEMBL24622046 0.84 ALPL (0.44) HPGDSMAPTTP53CASP3SENP8
SCHEMBL9937687 0.83 HPGDS (0.56) HPGDSMAPTTP53CASP3SENP8
SCHEMBL1359 0.83 ALPL (0.52) HPGDSMAPTTP53CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521410-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2026-01-13 US disclosed
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2024-06-06 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
EP-4139275-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF Syneurx International (Taiwan) Corp. (TW) 2023-03-01 EP disclosed
US-20220218730-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-07-14 US disclosed
US-20220218730-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-07-14 US disclosed
WO-2021213500-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220218730-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF HRH4, OR10J3, CYP3A5 HPGDS 4220/4885MAPT 2751/4885TP53 3288/4885
US-11793823-B2 Compounds and pharmaceutical uses thereof HRH4, OR10J3, CYP3A5 HPGDS 4220/4885MAPT 2751/4885TP53 3288/4885
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF HRH4, OR10J3, CYP3A5 HPGDS 4220/4885MAPT 2751/4885TP53 3288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.