Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469459 | 0.98 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1SMN1; SMN2MAPT | |
| SCHEMBL28061202 | 0.93 | ALDH1A1 (0.38) | ALDH1A1POLBHSD11B1SMN1; SMN2MAPT | |
| SCHEMBL17407230 | 0.80 | CYP1A2 (0.48) | POLBHSD11B1HTTHPGDMEN1 | |
| SCHEMBL27000251 | 0.78 | TSHR (0.55) | POLBSMN1; SMN2MAPTTSHRRAB9A | |
| SCHEMBL22322309 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1SMN1; SMN2MAPT | |
| SCHEMBL26614766 | 0.74 | DPP4 (0.36) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL14827284 | 0.73 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2MAPT | |
| SCHEMBL9987783 | 0.73 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2MAPT | |
| SCHEMBL304391 | 0.73 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2MAPT | |
| SCHEMBL3316653 | 0.73 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168009-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | Hangzhou DAC Biotech Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2021212638-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-28 | — | — | WO | disclosed |