Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808109 | 0.91 | DPP4 (0.41) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL17623403 | 0.81 | CHRNB2 (0.42) | DPP4DPP7DPP8DPP9POLB | |
| SCHEMBL20659907 | 0.79 | DPP4 (0.44) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL21138802 | 0.78 | ALDH1A1 (0.49) | DPP4DPP8DPP9ALDH1A1POLB | |
| SCHEMBL17623407 | 0.78 | ALDH1A1 (0.49) | DPP4DPP8DPP9ALDH1A1POLB | |
| SCHEMBL12524261 | 0.77 | MEN1 (0.55) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4934881 | 0.77 | MEN1 (0.55) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL2226544 | 0.77 | MEN1 (0.55) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL28061202 | 0.76 | ALDH1A1 (0.38) | MEN1MAPTKMT2AALDH1A1POLB | |
| SCHEMBL4469459 | 0.76 | ALDH1A1 (0.42) | MEN1MAPTKMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208092-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2023-11-02 | — | — | WO | disclosed |