Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | PRF1 | P14222 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492902 | 1.00 | MAPT (0.61) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL15192501 | 0.86 | MAPT (0.47) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL29440632 | 0.84 | MAOA (0.62) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL854664 | 0.84 | MAOA (0.62) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL23929409 | 0.83 | MAOA (0.56) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL3666440 | 0.81 | PRF1 (0.44) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL30169541 | 0.81 | PARP10 (0.50) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL2731697 | 0.81 | PARP10 (0.50) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL13992127 | 0.81 | METAP1 (0.43) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL1918267 | 0.78 | MAPK14 (0.55) | MAPTGAAMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4570901-A1 | METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS | Buddhist Tzu Chi Medical Foundation (TW) | 2025-06-18 | — | — | EP | claimed |
| US-20250188411-A1 | METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS | BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) | 2025-06-12 | — | — | US | claimed |
| US-9656927-B2 | Process for the synthesis of carboxylic acid derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-23 | — | — | US | claimed |
| US-20160272554-A1 | PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | claimed |
| WO-2015063798-A1 | A PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-05-07 | — | — | WO | claimed |
| CN-100516058-C | Process for synthesizing 5-cyanophthalide | UNIV ZHEJIANG (CN) | 2009-07-22 | — | — | CN | claimed |
| CN-100457747-C | Preparation process of key intermediate 5-cyanphthalide of antidepressant drug citalopram | UNIV ZHEJIANG (CN) | 2009-02-04 | — | — | CN | claimed |
| CN-1962651-A | Preparation process of key intermediate 5-cyanphthalide of antidepressant drug citalopram | UNIV ZHEJIANG (CN) | 2007-05-16 | — | — | CN | claimed |
| CN-1962652-A | Process for synthesizing 5-cyanophthalide | UNIV ZHEJIANG (CN) | 2007-05-16 | — | — | CN | claimed |
| US-20060009515-A1 | Process and intermediates for preparing escitalopram | TORCAN CHEMICAL LTD (CA) | 2006-01-12 | — | — | US | claimed |
| CN-1634906-A | Synthesis of 5-bromo phthalide | LINHAI XIANFENG CHEMICAL CO LT (CN) | 2005-07-06 | — | — | CN | claimed |
| EP-1495013-A1 | PROCESS AND INTERMEDIATES FOR PREPARING ESCITALOPRAM | TORCAN CHEMICAL Ltd (CA) | 2005-01-12 | — | — | EP | claimed |
| WO-2004089924-A1 | PROCESS FOR THE PREPARATION OF 5-BROMOPHTHALIDE | BROMINE COMPOUNDS LTD. (IL) | 2004-10-21 | — | — | WO | claimed |
| WO-2004065375-A1 | PROCESSES FOR THE PREPARATION OF ESCITALOPRAM AND ITS PRECURSOR | NATCO PHARMA LIMITED (IN) | 2004-08-05 | — | — | WO | claimed |
| WO-2003087081-A1 | PROCESS AND INTERMEDIATES FOR PREPARING ESCITALOPRAM | TORCAN CHEMICAL LTD. (CA) | 2003-10-23 | — | — | WO | claimed |
| EP-4736882-A2 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | Cullgen (Shanghai), Inc. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2026085629-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2026-04-30 | — | — | WO | disclosed |
| US-4665181-A | Anti-inflammatory phthalazinones | PENNWALT CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0164593-A1 | Anti-inflammatory phthalazinones | FISONS CORPORATION (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4136193-A | ANTI-DEPRESSIVE SUBSTITUTED 1-DIMETHYLAMINOPROPYL-1-PHENYL PHTHALANS | KEFALAS A/S (DK) | 1979-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272554-A1 | PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | PCCA, CPS1, CS | MAPT 2067/4885LMNA 3768/4885GAA 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.