SCHEMBL2392989

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9890707	0.83	ALDH1A1 (0.47)	ALDH1A1GAAKDM4ELMNAL3MBTL1
	SCHEMBL9890811	0.83	SLC6A4 (0.51)	ALDH1A1GAAKDM4ELMNAKMT2A
	SCHEMBL2393788	0.82	GAA (0.41)	ALDH1A1GAAKDM4ELMNAL3MBTL1
	SCHEMBL2395248	0.82	ALDH1A1 (0.42)	ALDH1A1GAAKDM4ELMNAL3MBTL1
	SCHEMBL2393913	0.80	MAPT (0.42)	ALDH1A1GAALMNAL3MBTL1KMT2A
	SCHEMBL2391917	0.80	GAA (0.42)	ALDH1A1GAALMNAL3MBTL1KMT2A
	SCHEMBL2395740	0.79	ALDH1A1 (0.40)	ALDH1A1GAAKDM4ELMNAL3MBTL1
	SCHEMBL17724584	0.74	ALDH1A1 (0.50)	ALDH1A1GAALMNAL3MBTL1KMT2A
	SCHEMBL19305429	0.74	ALDH1A1 (0.50)	ALDH1A1GAALMNAL3MBTL1KMT2A
	SCHEMBL9890656	0.74	CES2 (0.42)	ALDH1A1LMNAL3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.