Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 17/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023382 | 1.00 | CREBBP (0.39) | CREBBPBRD4EP300JAK2TYK2 | |
| SCHEMBL17785637 | 0.81 | CREBBP (0.50) | CREBBPBRD4EP300 | |
| SCHEMBL29403112 | 0.81 | CREBBP (0.50) | CREBBPBRD4EP300 | |
| SCHEMBL28649787 | 0.77 | CREBBP (0.41) | CREBBPBRD4EP300 | |
| SCHEMBL17785657 | 0.74 | CREBBP (0.47) | CREBBPBRD4EP300 | |
| SCHEMBL30853471 | 0.74 | MAPT (0.35) | CREBBPBRD4EP300 | |
| SCHEMBL23930147 | 0.74 | MAPT (0.35) | CREBBPBRD4EP300 | |
| SCHEMBL21255053 | 0.73 | CREBBP (0.43) | CREBBPBRD4EP300 | |
| SCHEMBL31692693 | 0.72 | KDM5B (0.38) | CREBBPBRD4EP300 | |
| SCHEMBL24258519 | 0.72 | PDE3B (0.41) | CREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397822-A | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2021213521-A1 | CBP/EP300 INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |