Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930147 | 1.00 | MAPT (0.35) | MAPTKDM4EALDH1A1LMNATP53 | |
| SCHEMBL24258519 | 0.82 | PDE3B (0.41) | MAPTKDM4EALDH1A1LMNATP53 | |
| SCHEMBL29403112 | 0.80 | CREBBP (0.50) | CREBBPBRD4EP300 | |
| SCHEMBL17785637 | 0.80 | CREBBP (0.50) | CREBBPBRD4EP300 | |
| SCHEMBL31565516 | 0.78 | MAPT (0.31) | MAPTKDM4EALDH1A1LMNATP53 | |
| SCHEMBL31565360 | 0.78 | AR (0.32) | MAPTKDM4EALDH1A1LMNATP53 | |
| SCHEMBL23930103 | 0.74 | CREBBP (0.39) | CREBBPBRD4EP300 | |
| SCHEMBL30023382 | 0.74 | CREBBP (0.39) | CREBBPBRD4EP300 | |
| SCHEMBL24316742 | 0.73 | CREBBP (0.52) | MAPTCREBBPBRD4EP300 | |
| SCHEMBL30992903 | 0.73 | CREBBP (0.41) | MAPTKDM4EGAACREBBPCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397822-B | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |