Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496189 | 0.83 | TBK1 (0.43) | CREBBPBRD4 | |
| SCHEMBL25198716 | 0.79 | CREBBP (0.41) | CREBBPBRD4EP300 | |
| SCHEMBL30395478 | 0.79 | CREBBP (0.41) | CREBBPBRD4EP300 | |
| SCHEMBL17785637 | 0.77 | CREBBP (0.50) | CREBBPBRD4EP300 | |
| SCHEMBL29403112 | 0.77 | CREBBP (0.50) | CREBBPBRD4EP300 | |
| SCHEMBL30023382 | 0.77 | CREBBP (0.39) | CREBBPBRD4EP300 | |
| SCHEMBL23930103 | 0.77 | CREBBP (0.39) | CREBBPBRD4EP300 | |
| SCHEMBL31692747 | 0.71 | GPR119 (0.42) | — | |
| SCHEMBL17785657 | 0.71 | CREBBP (0.47) | CREBBPBRD4EP300 | |
| SCHEMBL21255053 | 0.70 | CREBBP (0.43) | CREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507333-A | Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-113646002-A | Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degradation compounds and methods of use | 上海睿跃生物科技有限公司 | 2021-11-12 | — | — | CN | disclosed |