Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222643 | 0.78 | PTPN1 (0.50) | CES2CES1HSD17B14NPC1RAB9A | |
| SCHEMBL3221672 | 0.75 | SMN1; SMN2 (0.47) | CES2CES1HSD17B14NPC1RAB9A | |
| SCHEMBL855617 | 0.72 | CES2 (0.61) | CES2CES1GABBR2GABBR1GABRB1 | |
| SCHEMBL29772071 | 0.71 | CES2 (0.59) | CES2CES1GABBR2GABBR1GABRB1 | |
| SCHEMBL15120380 | 0.71 | CES2 (0.59) | CES2CES1GABBR2GABBR1GABRB1 | |
| SCHEMBL3957744 | 0.71 | CES2 (0.59) | CES2CES1GABBR2GABBR1GABRB1 | |
| SCHEMBL761473 | 0.71 | CES2 (0.59) | CES2CES1GABBR2GABBR1GABRB1 | |
| SCHEMBL758629 | 0.70 | CES2 (0.57) | CES2CES1GABBR2GABBR1GABRB1 | |
| SCHEMBL15385170 | 0.70 | CES2 (0.57) | CES2CES1GABBR2GABBR1GABRB1 | |
| SCHEMBL4307207 | 0.69 | CES1 (0.61) | CES2CES1GABBR2GABBR1HSD17B14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8021825-B2 | Optical waveguides and methods thereof | SUMITOMO BAKELITE CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |