Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922151 | 0.86 | PTPN1 (0.61) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL3222643 | 0.82 | PTPN1 (0.50) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL2393058 | 0.75 | CES2 (0.42) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL561093 | 0.75 | ALDH1A1 (0.61) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL564962 | 0.70 | HPGDS (0.53) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL28907353 | 0.69 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL13715355 | 0.68 | PTPN1 (0.67) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL1317943 | 0.68 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL30623333 | 0.68 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 | |
| SCHEMBL1974978 | 0.68 | PTPN1 (0.71) | SMN1; SMN2KDM4EHPGDPTPN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8200058-B2 | Light guide and light guide structure | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20100067861-A1 | LIGHT GUIDE AND LIGHT GUIDE STRUCTURE | SUMITOMO BAKELITE COMPANY LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |