SCHEMBL23930702

SCHEMBL23930702

Cc1ccc(C(c2ccc(C)cc2)C(Cl)(Cl)Cl)cc1.[SiH4]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.58
TDP1 Q9NUW8 3/20 0.58
LMNA P02545 3/20 0.58
MAPK1 P28482 2/20 0.58
HPGD P15428 2/20 0.58
TP53 P04637 1/20 0.58
HIF1A Q16665 1/20 0.58
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
ALDH1A1 P00352 5/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CHRNA7 P36544 1/20 0.41
ACHE P22303 5/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
POLB P06746 1/20 0.33
CYP19A1 P11511 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2362903 0.97 TSHR (0.61) TSHRTDP1LMNAMAPK1HPGD
SCHEMBL12319176 0.89 TSHR (0.78) TSHRTDP1LMNAMAPK1HPGD
SCHEMBL11858640 0.83 ALDH1A1 (0.85) TSHRTDP1LMNAMAPK1HPGD
SCHEMBL11849358 0.79 TSHR (0.55) TSHRTDP1LMNAMAPK1HPGD
SCHEMBL11289948 0.77 CHRNA7 (0.42) TSHRTDP1LMNAMAPK1HPGD
SCHEMBL11593534 0.77 CHRNA7 (0.42) TSHRTDP1LMNAMAPK1HPGD
Methoxychlor SCHEMBL27937411 0.75 MAPK1 (0.96) TSHRTDP1LMNAMAPK1HPGD
Chlorophenothane SCHEMBL2065589 0.74 TSHR (1.00) TSHRTDP1LMNAMAPK1HPGD
Chlorophenothane SCHEMBL7181 0.74 TSHR (1.00) TSHRTDP1LMNAMAPK1HPGD
Chlorophenothane SCHEMBL11570317 0.73 TSHR (0.86) TSHRTDP1LMNAMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4139318-A1 METHOD FOR THE DEHYDROGENATION AND METHYLATION OF SILANES WITH METHYL CHLORIDE Wacker Chemie AG (DE) 2023-03-01 EP disclosed
WO-2021213661-A1 METHOD FOR THE DEHYDROGENATION AND METHYLATION OF SILANES WITH METHYL CHLORIDE WACKER CHEMIE AG (DE) 2021-10-28 WO disclosed