Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930702 | 0.97 | TSHR (0.58) | TSHRTDP1LMNAMAPK1HPGD | |
| SCHEMBL12319176 | 0.91 | TSHR (0.78) | TSHRTDP1LMNAMAPK1HPGD | |
| SCHEMBL11858640 | 0.85 | ALDH1A1 (0.85) | TSHRTDP1LMNAMAPK1HPGD | |
| SCHEMBL11849358 | 0.81 | TSHR (0.55) | TSHRTDP1LMNAMAPK1HPGD | |
| SCHEMBL11593534 | 0.79 | CHRNA7 (0.42) | TSHRTDP1LMNAMAPK1HPGD | |
| SCHEMBL11289948 | 0.79 | CHRNA7 (0.42) | TSHRTDP1LMNAMAPK1HPGD | |
| Chlorophenothane SCHEMBL2065589 | 0.76 | TSHR (1.00) | TSHRTDP1LMNAMAPK1HPGD | |
| Chlorophenothane SCHEMBL7181 | 0.76 | TSHR (1.00) | TSHRTDP1LMNAMAPK1HPGD | |
| Chlorophenothane SCHEMBL11570317 | 0.75 | TSHR (0.86) | TSHRTDP1LMNAMAPK1HPGD | |
| SCHEMBL11302427 | 0.75 | HPGD (0.44) | TSHRTDP1LMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2568807-B1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | UNIV MISSISSIPPI STATE (US) | 2018-07-11 | — | — | EP | claimed |
| EP-1381576-B1 | A PROCESS FOR COATING A SILICEOUS SUBSTRATE WITH A SILICON CONTAINING LAYER | ICT COATINGS N V (BE) | 2005-03-23 | — | — | EP | claimed |
| US-12435377-B2 | Cancers with loss of chromosome 16Q and/or low expression of metallothionein proteins | THE BROAD INSTITUTE, INC. (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250281509-A1 | SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER | THE JOHNS HOPKINS UNIVERSTY | 2025-09-11 | — | — | US | disclosed |
| US-20250041316-A1 | METHODS AND COMPOSITIONS FOR TREATING LIVER DISEASE | UNIV TEMPLE (US) | 2025-02-06 | — | — | US | disclosed |
| CN-115873254-B | Silicone resin, preparation method and application | 杭州师范大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-116986967-A | Method for catalyzing carbon monoxide, methanol and methyl nitrite to synthesize dimethoxymethane and dimethyl carbonate in gas phase | 中国石油大学(华东) | 2023-11-03 | — | — | CN | disclosed |
| CN-109688807-B | Plants with increased herbicide tolerance | 巴斯夫欧洲公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-3467006-B1 | MIXTURES OF CYCLIC BRANCHED D/T-TYPE SILOXANES AND THEIR ENSUING PRODUCTS | EVONIK OPERATIONS GMBH (DE) | 2022-11-30 | — | — | EP | disclosed |
| WO-2020114609-A1 | PROCESS FOR REDUCING THE CONTENT OF BORON COMPOUNDS IN HALOSILANE-CONTAINING COMPOSITIONS | WACKER CHEMIE AG (DE) | 2020-06-11 | — | — | WO | disclosed |
| US-20120107725-A1 | Solid Polymer Electrolyte Composition, and Ion-Exchange Membrane, Membrane Electrode Assembly and Fuel Cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-1144736-B1 | AGGLOMERATION OF SILICON POWDERS | GE BAYER SILICONES GMBH & CO (DE) | 2004-08-25 | — | — | EP | disclosed |
| EP-1144736-A1 | AGGLOMERATION OF SILICON POWDERS | GE Bayer Silicones GmbH & Co. KG (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000037719-A1 | AGGLOMERATION OF SILICON POWDERS | GE BAYER SILICONES GMBH & CO. KG (DE) | 2000-06-29 | — | — | WO | disclosed |
| EP-0372341-A3 | METHOD FOR THE PREPARATION OF CHLORO-ORGANOSILANES | BAYER AG (DE) | 1991-03-27 | — | — | EP | disclosed |
| EP-0372341-A2 | Method for the preparation of chloro-organosilanes | BAYER AG (DE) | 1990-06-13 | — | — | EP | disclosed |
| EP-0305019-A1 | Process for the destruction of chemical waste materials, in particular of organic halogen compounds, by hydrogenolysis | Rijksuniversiteit Leiden (NL) | 1989-03-01 | — | — | EP | disclosed |
| EP-0269833-A2 | Silicon-containing polyamide compositions | BAYER AG (DE) | 1988-06-08 | — | — | EP | disclosed |
| US-3966824-A | BIODEGRADABLE INSECTICIDES | UNIVERSITY OF ILLINOIS FOUNDATION (US) | 1976-06-29 | — | — | US | disclosed |
| US-3941842-A | INSECTICIDE, LARVICIDE | THE UNIVERSITY OF ILLINOIS FOUNDATION (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250041316-A1 | METHODS AND COMPOSITIONS FOR TREATING LIVER DISEASE | LIPC, GYS2, FABP1 | TSHR 2840/4885TDP1 4811/4885LMNA 1042/4885 |
| US-12435377-B2 | Cancers with loss of chromosome 16Q and/or low expression of metallothionein proteins | GSTM2, GSTM1, AS3MT | TSHR 1484/4885TDP1 2079/4885LMNA 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.