SCHEMBL23930712

SCHEMBL23930712

N#Cc1c(Cl)nc(Cl)c2c1CCOC2

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.50
ALDH1A1 P00352 4/20 0.50
GAA P10253 2/20 0.50
HPGD P15428 2/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
KDM4E B2RXH2 2/20 0.47
NSD2 O96028 1/20 0.45
MAPK1 P28482 1/20 0.45
GLA P06280 2/20 0.44
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
HSD11B1 P28845 2/20 0.38
IDH1 O75874 6/20 0.36
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30110420 1.00 HTT (0.50) HTTALDH1A1GAAHPGDLMNA
SCHEMBL13329206 0.76 KDM4E (0.70) HTTALDH1A1GAAHPGDLMNA
SCHEMBL13329199 0.76 KDM4E (0.65) HTTALDH1A1GAAHPGDLMNA
SCHEMBL13329207 0.74 KDM4E (0.68) HTTALDH1A1GAAHPGDLMNA
SCHEMBL14250372 0.72 KDM4E (0.44) ALDH1A1HPGDKDM4EL3MBTL1HSD11B1
SCHEMBL3581242 0.69 IDH1 (0.36) HSD11B1IDH1
SCHEMBL24574853 0.69 WNT3A (0.32)
SCHEMBL30932866 0.69 WNT3A (0.32)
SCHEMBL13329195 0.68 ALDH1A1 (0.49) HTTALDH1A1GAAHPGDLMNA
SCHEMBL1338558 0.67 ALDH1A1 (0.51) HTTALDH1A1GAAHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667244-B 3-azabicycloalkyl derivatives and pharmaceutical compositions containing the same 株式会社LG化学 2024-04-12 CN disclosed
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
EP-4134366-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Lg Chem, Ltd. (KR) 2023-02-15 EP disclosed
CN-115667244-A 3-azabicycloalkyl derivatives and pharmaceutical compositions comprising the same 株式会社LG化学 2023-01-31 CN disclosed
WO-2021215765-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 주식회사 엘지화학 (KR) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADCY1, ADCY7 HTT 2025/4885ALDH1A1 1538/4885GAA 2413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.