SCHEMBL23930947

SCHEMBL23930947

C=Cc1nc(C(F)(F)F)c(C(=O)NC2CN(C(=O)OC(C)(C)C)C2)n1C(C)C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.41
HDAC4 P56524 3/20 0.39
HDAC6 Q9UBN7 2/20 0.39
POLR1A O95602 1/20 0.38
DHODH Q02127 1/20 0.38
USP30 Q70CQ3 9/20 0.37
ADORA2A P29274 2/20 0.36
ADORA2B P29275 2/20 0.36
PARP1 P09874 2/20 0.35
EGFR P00533 1/20 0.34
ERBB2 P04626 1/20 0.34
ERBB3 P21860 1/20 0.34
ERBB4 Q15303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29902359 0.91 NR1H2 (0.42) NR1H2HDAC4HDAC6POLR1ADHODH
SCHEMBL21879961 0.87 KRAS (0.31)
SCHEMBL23930955 0.79 PARP1 (0.38) NR1H2HDAC4HDAC6POLR1ADHODH
SCHEMBL23930996 0.79 ADORA2A (0.40) HDAC4HDAC6POLR1AUSP30ADORA2A
SCHEMBL21880034 0.78 ADORA2A (0.38) HDAC4HDAC6POLR1ADHODHUSP30
SCHEMBL23421445 0.78 NR1H2 (0.30) NR1H2
SCHEMBL23930974 0.78 ADORA2A (0.37) NR1H2HDAC4HDAC6POLR1ADHODH
SCHEMBL24126467 0.77 ADORA2A (0.42) HDAC4HDAC6POLR1AUSP30ADORA2A
SCHEMBL24126928 0.75 POLR1A (0.42) HDAC4HDAC6POLR1ADHODHUSP30
SCHEMBL23930946 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO. LTD. (JP) 2023-02-16 US disclosed
EP-4067343-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2022-10-05 EP disclosed
WO-2021215545-A1 ANTICANCER COMBINATION THERAPY WITH N-(1-ACRYLOYL-AZETIDIN-3-YL)-2-((1H-INDAZOL-3-YL)AMINO)METHYL)-1H-IMIDAZOLE-5-CARBOXAMIDE INHIBITOR OF KRAS-G12C TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB NR1H2 399/4885HDAC4 750/4885HDAC6 2020/4885
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF MYB, MLX, EP300 NR1H2 430/4885HDAC4 617/4885HDAC6 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.