Sugi Predict

Sugi Predict / Compounds / SCHEMBL2393111

SCHEMBL2393111

SCHEMBL2393111

CNC(=O)c1nc(C(=O)NC)nc(C(=O)NC)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC2 Q92769 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ PLK1 P53350 6/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ GAA P10253 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ MCL1 Q07820 1/20 0.37
▸ HPGD P15428 3/20 0.36
▸ TSHR P16473 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ BAZ2B Q9UIF8 1/20 0.35
▸ MMP2 P08253 1/20 0.35
▸ MMP3 P08254 1/20 0.35
▸ MMP8 P22894 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17580070 0.82 PLK1 (0.37) HDAC2HDAC8HDAC6SMN1; SMN2ALDH1A1
SCHEMBL12914934 0.80 CDC7 (0.38) HDAC2HDAC8HDAC6PLK1L3MBTL1
SCHEMBL31312412 0.78 S1PR2 (0.42) HDAC2HDAC8HDAC6SMN1; SMN2ALDH1A1
SCHEMBL15495237 0.73 CDC7 (0.33) HDAC2HDAC8HDAC6
SCHEMBL2363536 0.73 P2RX7 (0.60) HDAC2HDAC8HDAC6ALDH1A1KDM4E
SCHEMBL20320399 0.71 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1KDM4EPLK1L3MBTL1
SCHEMBL3679773 0.71 PLK1 (0.53) HDAC8HDAC6ALDH1A1KDM4EPLK1
SCHEMBL9948788 0.71 P2RX7 (0.37) HDAC2HDAC8HDAC6SMN1; SMN2PLK1
SCHEMBL15658109 0.70 SMYD3 (0.41) KDM4E
Hydrochloric Acid SCHEMBL28281828 0.70 SMYD3 (0.51) HDAC6SMN1; SMN2ALDH1A1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191460-B1 PROCESS FOR THE PREPARATION OF TRIAZINE CARBAMATES ALLNEX NETHERLANDS BV (NL) 2020-01-29 — — EP disclosed
US-10071972-B2 Process for the preparation of triazine carbamates ALLNEX NETHERLANDS B.V. (NL) 2018-09-11 — — US disclosed
US-20170233353-A1 PROCESS FOR THE PREPARATION OF TRIAZINE CARBAMATES ALLNEX IP S.À.R.L. (LU) 2017-08-17 — — US disclosed
EP-3191460-A1 PROCESS FOR THE PREPARATION OF TRIAZINE CARBAMATES Allnex IP S.à.r.l. (LU) 2017-07-19 — — EP disclosed
WO-2016037973-A1 PROCESS FOR THE PREPARATION OF TRIAZINE CARBAMATES ALLNEX IP S.À.R.L. (LU) 2016-03-17 — — WO disclosed
EP-2995613-A1 Process for the preparation of triazine carbamates Allnex IP S.à.r.l. (LU) 2016-03-16 — — EP disclosed
EP-2931811-A2 (METH)ACRYLATED AMINO RESINS BASF SE (DE) 2015-10-21 — — EP disclosed
WO-2014090647-A2 (METH)ACRYLATED AMINO RESINS BASF SE (DE) 2014-06-19 — — WO disclosed
US-8742003-B2 Silylated amino resins BASF SE (DE) 2014-06-03 — — US disclosed
US-20140066552-A1 SILYLATED AMINO RESINS BASF SE (DE) 2014-03-06 — — US disclosed
US-20130005204-A1 SILYLATED AMINO RESINS BASF SE (DE) 2013-01-03 — — US disclosed
US-8309649-B2 Silylated amino resins BASF SE (DE) 2012-11-13 — — US disclosed
EP-1740555-B1 RADIATION CURABLE 1,3,5-TRIAZINE CARBAMATES AND 1,3,5-TRIAZINE UREAS CONTAINING VINYL GROUPS, METHACRYLOYL GROUPS, OR ACRYLOYL GROUPS BASF SE (DE) 2012-06-13 — — EP disclosed
US-8044197-B2 Radiation curable 1,3,5-triazine carbamates and 1,3,5-triazine ureas containing vinyl groups, methacryloyl groups, or acryloyl groups BASF SE (DE) 2011-10-25 — — US disclosed
US-20110213068-A1 SILYLATED AMINO RESINS BASF SE (DE) 2011-09-01 — — US disclosed
EP-1737834-B1 METHOD FOR PRODUCING 1,3,5-TRIAZINE CARBAMATES AND UREAS BASF AG (DE) 2007-10-03 — — EP disclosed
US-20070208101-A1 Radiation Curable 1,3,5-Triazine Carbamates and 1,3,5-Triazine Ureas Containing Vinyl Groups, Methacryloyl Groups, or Acryloyl Groups BASF AKIENGESELLSCHARFT (DE) 2007-09-06 — — US disclosed
US-20070196668-A1 Method For Producing 1,3,5-Triazine Carbamates And Ureas BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 — — US disclosed
EP-1737834-A1 METHOD FOR PRODUCING 1,3,5-TRIAZINE CARBAMATES AND UREAS BASF AKTIENGESELLSCHAFT (DE) 2007-01-03 — — EP disclosed
WO-2005100328-A1 METHOD FOR PRODUCING 1,3,5-TRIAZINE CARBAMATES AND UREAS BASF AKTIENGESELLSCHAFT (DE) 2005-10-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196668-A1 Method For Producing 1,3,5-Triazine Carbamates And Ureas USP5, UMPS, UTS2R HDAC2 889/4885HDAC8 1473/4885HDAC6 573/4885
US-20070208101-A1 Radiation Curable 1,3,5-Triazine Carbamates and 1,3,5-Triazine Ureas Containing Vinyl Groups, Methacryloyl Groups, or Acryloyl Groups USP5, XRCC5, USP25 HDAC2 525/4885HDAC8 718/4885HDAC6 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.