SCHEMBL23932105

SCHEMBL23932105

CCCN(c1ccc2ncc(Br)n2n1)C1CCOCC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 14/20 0.35
MKNK1 Q9BUB5 4/20 0.35
DYRK1A Q13627 1/20 0.34
FYN P06241 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932182 0.91 MKNK1 (0.36) CRHR1MKNK1DYRK1AFYN
SCHEMBL23931871 0.85 MKNK1 (0.36) CRHR1MKNK1DYRK1AFYN
SCHEMBL23931891 0.82 SMN1; SMN2 (0.40) MKNK1DYRK1AFYN
SCHEMBL23931923 0.76 PIM1 (0.47) MKNK1FYN
SCHEMBL23932000 0.75 HCAR3 (0.41) MKNK1
SCHEMBL15254587 0.70 MKNK1 (0.44) MKNK1
SCHEMBL23932033 0.70 FFAR2 (0.34)
SCHEMBL23931998 0.69 SMN1; SMN2 (0.52)
SCHEMBL20119801 0.69 NTRK1 (0.39) MKNK1
SCHEMBL23931849 0.68 PIM1 (0.48) MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435091-B2 RNA-binding protein multimerization inhibitors and methods of use thereof THE UAB RESEARCH FOUNDATION (US) 2025-10-07 US disclosed
US-20230159542-A1 RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF THE UAB RESEARCH FOUNDATION (US) 2023-05-25 US disclosed
WO-2021216757-A1 RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF THE UAB RESEARCH FOUNDATION (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159542-A1 RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF HNRNPR, HNRNPAB, RBM3 CRHR1 2009/4885MKNK1 1675/4885DYRK1A 3007/4885
US-12435091-B2 RNA-binding protein multimerization inhibitors and methods of use thereof HNRNPR, HNRNPAB, RBM3 CRHR1 2009/4885MKNK1 1675/4885DYRK1A 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.