SCHEMBL2393252

SCHEMBL2393252

NC(N)=Nc1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28834416 0.98 HSD17B10 (0.41)
Sulfuric Acid SCHEMBL28785882 0.90 ACP1 (0.37)
SCHEMBL16571551 0.83
SCHEMBL10822282 0.79 ALDH1A1 (0.38)
SCHEMBL27309845 0.79 NPC1 (0.48)
Isonicotinonitrile SCHEMBL27313121 0.79 PLG (0.39)
Hydrochloric Acid SCHEMBL27338798 0.78 NPC1 (0.47)
SCHEMBL27336554 0.78 ADRA2A (0.41)
SCHEMBL8932378 0.77
SCHEMBL1258975 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108715721-B Signature coating, signature film and preparation method thereof, and in-mold label film and preparation method thereof 深圳市深大极光科技股份有限公司 2024-03-22 CN claimed
WO-2023003497-A1 COMPOUNDS WITH LYSOSOMOTROPIC AND ANTIVIRAL ACTIVITY ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ВАЛЕНТА-ИНТЕЛЛЕКТ" 2023-01-26 WO claimed
WO-2021183259-A1 FAMOTIDINE AND FAMOTIDINE ANALOGS FOR CORONA VIRUS TREATMENT Nanopharmaceutics, Inc. (US) 2021-09-16 WO claimed
CN-108715721-A A kind of signature coating, signature film and preparation method thereof, in-mold label film and preparation method thereof 深圳市深大极光科技有限公司 2018-10-30 CN claimed
CN-101684083-B Guanidyl alkanoylamino substituted tetracycline derivative SHANDONG XUANZHU MEDICINE TECHNOLOGY CO LTD 2011-10-05 CN claimed
CN-101117538-B Ink absorption layer composition and ink absorption layer sign strip produced thereby CHINESE BANKNOTE PRINTING AND MINTING CORP 2010-07-28 CN claimed
CN-101759604-A Guanidyl substitutional tetracycline derivative SHANDONG XUANZHU PHARM TECH CO 2010-06-30 CN claimed
CN-101684083-A Guanidyl alkanoylamino substituted tetracycline derivative SHANDONG XUANZHU MEDICINE TECH 2010-03-31 CN claimed
CN-101117538-A Ink absorption layer composition and ink absorption layer sign strip produced thereby CHINESE BANKNOTE PRINTING AND (CN) 2008-02-06 CN claimed
WO-2007081530-A2 ENDOLUMINAL MEDICAL DEVICE FOR LOCAL DELIVERY OF CATHEPSIN INHIBITORS MED INSTITUTE, INC. (US) 2007-07-19 WO claimed
EP-1534278-A4 NITROSATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE NITROMED INC (US) 2006-09-06 EP claimed
JP-2005539013-A 2005-12-22 JP claimed
EP-1534278-A2 NITROSATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE Nitromed, Inc. (US) 2005-06-01 EP claimed
WO-2004012659-A2 NITROSATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2004-02-12 WO claimed
US-20040024014-A1 Nitrosated proton pump inhibitors, compositions and methods of use NITROMED, INC. (US) 2004-02-05 US claimed
US-4293549-A Quinolinyl guanidines having antiinflammatory, analgesic or antipyretic activity LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTION-SAKTIESELSKAB) (DK) 1981-10-06 US claimed
CN-108715721-B Signature coating, signature film and preparation method thereof, and in-mold label film and preparation method thereof 深圳市深大极光科技股份有限公司 2024-03-22 CN disclosed
CN-110546136-B Proline-based neuropeptide FF receptor modulators 研究三角协会 2023-07-18 CN disclosed
CN-1079469-A Preparation method with thiazole derivative of antiulcer activity and Histamine Receptors antagonistic action FUJISAWA PHARMACEUTICAL CO (JP) 1993-12-15 CN disclosed
CN-1040796-A The preparation method of fruylthiazole derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1990-03-28 CN disclosed