Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ATP4A | P20648 | 5/20 | 0.35 |
| ▸ | ATP4B | P51164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335367 | 0.81 | CASP1 (0.40) | ADRA2AADRA2BADRA2CPLAUATP4A | |
| Hydrochloric Acid SCHEMBL27316061 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1L3MBTL1ALDH1A1 | |
| SCHEMBL2393252 | 0.78 | — | — | |
| SCHEMBL27314194 | 0.77 | PKM (0.53) | LMNASMN1; SMN2MAPTALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL28834416 | 0.77 | HSD17B10 (0.41) | ADRA2AADRA2BADRA2CPLAULMNA | |
| SCHEMBL27309845 | 0.76 | NPC1 (0.48) | ADRA2AADRA2BADRA2CPLAULMNA | |
| SCHEMBL27313123 | 0.76 | LMNA (0.44) | LMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL27325450 | 0.75 | TSHR (0.52) | LMNASMN1; SMN2MAPTALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL27338798 | 0.75 | NPC1 (0.47) | ADRA2AADRA2BADRA2CPLAULMNA | |
| SCHEMBL215763 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050191-A | New thiazole derivative, they the preparation method and contain their pharmaceutical composition | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-03-27 | — | — | CN | disclosed |