SCHEMBL23933201

SCHEMBL23933201

CONc1c(C)c(C)cc(C)c1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14995938 0.74 RAPGEF4 (0.55) RAPGEF4
SCHEMBL29196018 0.71 RAPGEF4 (0.50) RAPGEF4
SCHEMBL4084555 0.69 RAPGEF4 (0.35) RAPGEF4
SCHEMBL4557600 0.67 CYP3A4 (0.35) RAPGEF4
SCHEMBL9643643 0.67 RAPGEF4 (0.33) RAPGEF4
Hydrochloric Acid SCHEMBL28693065 0.65 RAPGEF4 (0.32) RAPGEF4
SCHEMBL2633660 0.63 ALDH1A1 (0.59) TUBB1
SCHEMBL5566891 0.63 ACHE (0.43) TUBB1
SCHEMBL120101 0.62 TSHR (0.39) RAPGEF4
SCHEMBL21459249 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158802-A1 MRNA TREATMENT NANOPARTICLES MEDICI THERAPEUTICS, INC. 2024-05-16 US disclosed
US-11879126-B2 MRNA treatment nanoparticles NUTCRACKER THERAPEUTICS, INC. (US) 2024-01-23 US disclosed
US-20230193288-A1 MRNA TREATMENT NANOPARTICLES MEDICI THERAPEUTICS, INC. 2023-06-22 US disclosed
EP-4139044-A1 MRNA TREATMENT NANOPARTICLES Nutcracker Therapeutics, Inc. (US) 2023-03-01 EP disclosed
WO-2021216647-A1 MRNA TREATMENT NANOPARTICLES NUTCRACKER THERAPEUTICS, INC. (US) 2021-10-28 WO disclosed