SCHEMBL2393322

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2393733	0.91	NR3C1 (0.59)	ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL2395408	0.90	PGR (0.49)	NR3C1PGRARESR1ESR2
	SCHEMBL452017	0.89	PGR (0.47)	NR3C1PGRARESR1ESR2
	SCHEMBL2397801	0.88	PGR (0.52)	ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL2407661	0.86	NR3C1 (0.58)	ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL2391896	0.84	PGR (0.43)	ALDH1A1HPGDHSD17B10NR3C1PGR
	SCHEMBL448647	0.83	NR3C1 (0.49)	NR3C1PGRARESR1ESR2
	SCHEMBL446861	0.83	PGR (0.51)	NR3C1PGRARESR1ESR2
	SCHEMBL2398191	0.83	NR3C1 (0.49)	NR3C1PGRARESR1ESR2
	SCHEMBL449839	0.83	PGR (0.49)	NR3C1PGRARESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.