SCHEMBL2393733

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2393322	0.91	ALDH1A1 (0.53)	NR3C1ALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL2396093	0.86	PGR (0.58)	NR3C1ALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL2392249	0.83	NR3C1 (0.53)	NR3C1NR3C2ARPGR
	SCHEMBL2390510	0.83	NR3C1 (0.50)	NR3C1ALDH1A1CYP3A4HPGDHSD17B10
	SCHEMBL2545912	0.82	NR3C1 (0.48)	NR3C1NR3C2ARPGR
	SCHEMBL2398293	0.82	NR3C1 (0.48)	NR3C1ALDH1A1CYP3A4HSD17B10NR3C2
	SCHEMBL2395408	0.81	PGR (0.49)	NR3C1NR3C2ARPGR
	SCHEMBL2391752	0.81	NR3C1 (0.52)	NR3C1NR3C2ARPGR
	SCHEMBL449529	0.81	NR3C1 (0.47)	NR3C1NR3C2ARPGR
	SCHEMBL2396425	0.80	NR3C1 (0.51)	NR3C1NR3C2ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.