Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PLK1 | P53350 | 8/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250247 | 0.89 | HDAC6 (0.80) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL2425658 | 0.85 | HDAC2 (0.67) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL14115137 | 0.82 | HDAC6 (0.70) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL16198923 | 0.82 | HDAC6 (0.70) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL159659 | 0.80 | HDAC2 (0.67) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL19631295 | 0.80 | HDAC6 (1.00) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL131434 | 0.80 | MMP13 (0.77) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL2643668 | 0.80 | HDAC8 (0.67) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL479724 | 0.80 | HDAC2 (0.67) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL18821524 | 0.79 | SMN1; SMN2 (0.59) | HDAC8HDAC6HDAC2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |