Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992082 | 0.87 | MEN1 (0.34) | HSD11B1MEN1KMT2AALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL23933225 | 0.86 | ALDH1A1 (0.33) | HSD11B1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL23933252 | 0.77 | ALDH1A1 (0.40) | HSD11B1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL23992023 | 0.75 | — | — | |
| SCHEMBL23992080 | 0.74 | SCN9A (0.34) | HSD11B1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL23933254 | 0.74 | ALDH1A1 (0.36) | HSD11B1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL18262007 | 0.68 | TDP1 (0.50) | MEN1KMT2A | |
| SCHEMBL18262010 | 0.68 | TDP1 (0.50) | MEN1KMT2A | |
| SCHEMBL18487257 | 0.68 | TDP1 (0.50) | MEN1KMT2A | |
| SCHEMBL23992105 | 0.68 | THRB (0.36) | ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |