Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065758 | 0.84 | HTR2C (0.77) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL4068122 | 0.81 | HTR2C (0.68) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL2532290 | 0.81 | HTR2C (0.72) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL16457233 | 0.81 | HTR2C (0.72) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL31087548 | 0.79 | HTR2C (0.70) | HTR2CDRD2HTR2AHTR2B | |
| Cyanide SCHEMBL27792102 | 0.79 | HTR2C (0.70) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL5668848 | 0.79 | HTR2C (0.70) | HTR2CDRD2HTR2AHTR2B | |
| SCHEMBL17729642 | 0.79 | HTR2C (0.70) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL27343752 | 0.78 | HTR2C (0.54) | HTR2CDRD2HTR2AHTR2BHTR1A | |
| SCHEMBL24065185 | 0.78 | HTR2C (0.58) | HTR2CDRD2HTR2AHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |