SCHEMBL27343752

SCHEMBL27343752

FC(F)(F)c1cccc(C2[CH]C2)c1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.54
HTR2A P28223 2/20 0.50
HTR2B P41595 2/20 0.50
HTR1A P08908 1/20 0.47
KDM1A O60341 4/20 0.46
RCOR1 Q9UKL0 1/20 0.46
DRD2 P14416 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28176930 0.79 HTR2C (0.46) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL23933264 0.78 HTR2C (0.62) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL1065758 0.78 HTR2C (0.77) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL427827 0.76 HTR2C (0.58) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL12472855 0.76 HTR2C (0.50) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL27848063 0.75 HTR2C (0.50) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL6492774 0.74 HTR1A (0.62) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL5698951 0.74 HTR1A (0.62) HTR2CHTR2AHTR2BHTR1AKDM1A
SCHEMBL16457233 0.74 HTR2C (0.72) HTR2CHTR2AHTR2BHTR1ADRD2
SCHEMBL29990806 0.74 HTR2C (0.57) HTR2CHTR2AHTR2BHTR1AKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1045576-A Pesticide WELLCOME FOUND (GB) 1990-09-26 CN disclosed